Cargando…

Needle in a Haystack: The Naïve Repertoire as a Source of T Cell Receptors for Adoptive Therapy with Engineered T Cells

T cell engineering with antigen-specific T cell receptors (TCRs) has allowed the generation of increasingly specific, reliable, and versatile T cell products with near-physiological features. However, a broad applicability of TCR-based therapies in cancer is still limited by the restricted number of...

Descripción completa

Detalles Bibliográficos
Autores principales: D’Ippolito, Elvira, Wagner, Karolin I., Busch, Dirk H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664211/
https://www.ncbi.nlm.nih.gov/pubmed/33171940
http://dx.doi.org/10.3390/ijms21218324