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Ring trial of 2nd generation RT‐QuIC diagnostic tests for sporadic CJD

OBJECTIVE: Real‐time quaking‐induced conversion (RT‐QuIC) assays detect prion‐seeding activity in a variety of human biospecimens, including cerebrospinal fluid and olfactory mucosa swabs. The assay has shown high diagnostic accuracy in patients with prion disorders. Recently, advances in these test...

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Detalles Bibliográficos
Autores principales: Orrú, Christina D., Groveman, Bradley R., Foutz, Aaron, Bongianni, Matilde, Cardone, Franco, McKenzie, Neil, Culeux, Audrey, Poleggi, Anna, Grznarova, Katarina, Perra, Daniela, Fiorini, Michele, Liu, Xiaoqin, Ladogana, Anna, Sbriccoli, Marco, Hughson, Andrew G., Haïk, Stéphane, Green, Alison J., Geschwind, Michael D., Pocchiari, Maurizio, Safar, Jiri G., Zanusso, Gianluigi, Caughey, Byron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664259/
https://www.ncbi.nlm.nih.gov/pubmed/33185334
http://dx.doi.org/10.1002/acn3.51219