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RAC1 nitration at Y(32) IS involved in the endothelial barrier disruption associated with lipopolysaccharide-mediated acute lung injury

Acute lung injury (ALI), a devastating illness induced by systemic inflammation e.g., sepsis or local lung inflammation e.g., COVID-19 mediated severe pneumonia, has an unacceptably high mortality and has no effective therapy. ALI is associated with increased pulmonary microvascular hyperpermeabilit...

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Detalles Bibliográficos
Autores principales: Wang, Ting, Yegambaram, Manivannan, Gross, Christine, Sun, Xutong, Lu, Qing, Wang, Hui, Wu, Xiaomin, Kangath, Archana, Tang, Haiyang, Aggarwal, Saurabh, Black, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664366/
https://www.ncbi.nlm.nih.gov/pubmed/33248422
http://dx.doi.org/10.1016/j.redox.2020.101794