Cargando…

RAC1 nitration at Y(32) IS involved in the endothelial barrier disruption associated with lipopolysaccharide-mediated acute lung injury

Acute lung injury (ALI), a devastating illness induced by systemic inflammation e.g., sepsis or local lung inflammation e.g., COVID-19 mediated severe pneumonia, has an unacceptably high mortality and has no effective therapy. ALI is associated with increased pulmonary microvascular hyperpermeabilit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Ting, Yegambaram, Manivannan, Gross, Christine, Sun, Xutong, Lu, Qing, Wang, Hui, Wu, Xiaomin, Kangath, Archana, Tang, Haiyang, Aggarwal, Saurabh, Black, Stephen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664366/ https://www.ncbi.nlm.nih.gov/pubmed/33248422 http://dx.doi.org/10.1016/j.redox.2020.101794

Ejemplares similares

Activation of the mechanosensitive Ca(2+) channel TRPV4 induces endothelial barrier permeability via the disruption of mitochondrial bioenergetics
por: Lu, Qing, et al.
Publicado: (2020)

The mitochondrial redistribution of eNOS is involved in lipopolysaccharide induced inflammasome activation during acute lung injury
por: Wang, Hui, et al.
Publicado: (2021)

Nitration of protein kinase G-Iα modulates cyclic nucleotide crosstalk via phosphodiesterase 3A: Implications for acute lung injury
por: Zemskov, Evgeny A., et al.
Publicado: (2021)

TGF-β1 attenuates mitochondrial bioenergetics in pulmonary arterial endothelial cells via the disruption of carnitine homeostasis
por: Sun, Xutong, et al.
Publicado: (2020)

Endothelial Nitric Oxide Synthase Deficient Mice Are Protected from Lipopolysaccharide Induced Acute Lung Injury
por: Gross, Christine M., et al.
Publicado: (2015)

Mitochondrial Metabolism, Redox, and Calcium Homeostasis in Pulmonary Arterial Hypertension
por: Liang, Shuxin, et al.
Publicado: (2022)

Role of Environmental Contaminants in the Etiology of Alzheimer's Disease: A Review
por: Manivannan, Yegambaram, et al.
Publicado: (2015)

Synergism of MSC-secreted HGF and VEGF in stabilising endothelial barrier function upon lipopolysaccharide stimulation via the Rac1 pathway
por: Yang, Yi, et al.
Publicado: (2015)

Blood-Brain Barrier Disruption by Lipopolysaccharide and Sepsis-Associated Encephalopathy
por: Peng, Xiaoyao, et al.
Publicado: (2021)

Loss of SOX18/CLAUDIN5 disrupts the pulmonary endothelial barrier in ventilator-induced lung injury
por: Garcia-Flores, Alejandro E., et al.
Publicado: (2022)

NF-κB-dependent repression of Sox18 transcription factor requires the epigenetic regulators histone deacetylases 1 and 2 in acute lung injury
por: Zemskov, Evgeny A., et al.
Publicado: (2022)

Nitrate partially inhibits lipopolysaccharide-induced inflammation by maintaining mitochondrial function
por: Yang, Yang, et al.
Publicado: (2020)

Lipopolysaccharide Disrupts the Milk-Blood Barrier by Modulating Claudins in Mammary Alveolar Tight Junctions
por: Kobayashi, Ken, et al.
Publicado: (2013)

Glutathione Supplementation Attenuates Lipopolysaccharide-Induced Mitochondrial Dysfunction and Apoptosis in a Mouse Model of Acute Lung Injury
por: Aggarwal, Saurabh, et al.
Publicado: (2012)

Regulation of Thrombin-Induced Lung Endothelial Cell Barrier Disruption by Protein Kinase C Delta
por: Xie, Lishi, et al.
Publicado: (2016)

Complex interplay between autophagy and oxidative stress in the development of pulmonary disease
por: Ornatowski, Wojciech, et al.
Publicado: (2020)

Propionate Protects against Lipopolysaccharide-Induced Mastitis in Mice by Restoring Blood–Milk Barrier Disruption and Suppressing Inflammatory Response
por: Wang, Jingjing, et al.
Publicado: (2017)

Disruption of the rice nitrate transporter OsNPF2.2 hinders root-to-shoot nitrate transport and vascular development
por: Li, Yuge, et al.
Publicado: (2015)

Particulate matter disrupts human lung endothelial cell barrier integrity via Rho-dependent pathways
por: Wang, Ting, et al.
Publicado: (2017)

Lipopolysaccharide-induced blood-brain barrier disruption: roles of cyclooxygenase, oxidative stress, neuroinflammation, and elements of the neurovascular unit
por: Banks, William A., et al.
Publicado: (2015)

PKC-Dependent Phosphorylation of eNOS at T495 Regulates eNOS Coupling and Endothelial Barrier Function in Response to G(+) -Toxins
por: Chen, Feng, et al.
Publicado: (2014)

Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes
por: Scala, Marcello, et al.
Publicado: (2022)

RhoB controls endothelial barrier recovery by inhibiting Rac1 trafficking to the cell border
por: Marcos-Ramiro, Beatriz, et al.
Publicado: (2016)

Site‐specific and endothelial‐mediated dysfunction of the alveolar‐capillary barrier in response to lipopolysaccharides
por: Janga, Harshavardhan, et al.
Publicado: (2017)

Nitric oxide induces hypoxia ischemic injury in the neonatal brain via the disruption of neuronal iron metabolism
por: Lu, Qing, et al.
Publicado: (2015)

Epidermal growth factor attenuates blood‐spinal cord barrier disruption via PI3K/Akt/Rac1 pathway after acute spinal cord injury
por: Zheng, Binbin, et al.
Publicado: (2016)

Semen Ziziphi Spinosae attenuates blood–brain barrier dysfunction induced by lipopolysaccharide by targeting the FAK-DOCK180-Rac1-WAVE2-Arp3 signaling pathway
por: Liu, Huayan, et al.
Publicado: (2022)

Role of Carnitine Acetyl Transferase in Regulation of Nitric Oxide Signaling in Pulmonary Arterial Endothelial Cells
por: Sharma, Shruti, et al.
Publicado: (2012)

Interaction between mitochondrial homeostasis and barrier function in lipopolysaccharide‐induced endothelial cell injury
por: Zhu, Weiwei, et al.
Publicado: (2023)

The redox mechanism for vascular barrier dysfunction associated with metabolic disorders: Glutathionylation of Rac1 in endothelial cells
por: Han, Jingyan, et al.
Publicado: (2016)

Lead exposure induces nitrative stress and disrupts ribbon synapses in the cochlea
por: Rosati, Rita, et al.
Publicado: (2022)

MgcRacGAP interacts with cingulin and paracingulin to regulate Rac1 activation and development of the tight junction barrier during epithelial junction assembly
por: Guillemot, Laurent, et al.
Publicado: (2014)

Epithelial RAC1 niches in IBD: from barrier integrity to cytoskeletal plasticity
por: Haag, Lea-Maxie, et al.
Publicado: (2023)

Nitration of 5,11-dihydroindolo[3,2-b]carbazoles and synthetic applications of their nitro-substituted derivatives
por: Irgashev, Roman A, et al.
Publicado: (2017)

Positive Feedback Regulation of Proliferation in Vascular Smooth Muscle Cells Stimulated by Lipopolysaccharide Is Mediated through the TLR 4/Rac1/Akt Pathway
por: Jiang, Dehua, et al.
Publicado: (2014)

Disrupted-in-Schizophrenia-1 (DISC1) regulates spines of the glutamate synapse via Rac1
por: Hayashi-Takagi, Akiko, et al.
Publicado: (2010)

Activation of RhoA, but Not Rac1, Mediates Early Stages of S1P-Induced Endothelial Barrier Enhancement
por: Zhang, Xun E., et al.
Publicado: (2016)

Epac1 Is Crucial for Maintenance of Endothelial Barrier Function through A Mechanism Partly Independent of Rac1
por: García-Ponce, Alexander, et al.
Publicado: (2020)

PbrSLAH3 is a nitrate-selective anion channel which is modulated by calcium-dependent protein kinase 32 in pear
por: Chen, Guodong, et al.
Publicado: (2019)

Hantavirus-induced disruption of the endothelial barrier: neutrophils are on the payroll
por: Schönrich, Günther, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_fati3p58m8gaphnsccqna4dgj8