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Differential effects of cotreatment of the antibiotic rifampin with host-directed therapeutics in reducing intracellular Staphylococcus aureus infection

BACKGROUND: Chronic infection by Staphylococcus aureus drives pathogenesis in important clinical settings, such as recurrent pulmonary infection in cystic fibrosis and relapsing infection in osteomyelitis. Treatment options for intracellular S. aureus infection are limited. Rifampin, a lipophilic an...

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Detalles Bibliográficos
Autores principales: Evans, Melissa D., Sammelson, Robert, McDowell, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664464/
https://www.ncbi.nlm.nih.gov/pubmed/33240647
http://dx.doi.org/10.7717/peerj.10330