Hypoxia and metabolic inhibitors alter the intracellular ATP:ADP ratio and membrane potential in human coronary artery smooth muscle cells

ATP-sensitive potassium (K(ATP)) channels couple cellular metabolism to excitability, making them ideal candidate sensors for hypoxic vasodilation. However, it is still unknown whether cellular nucleotide levels are affected sufficiently to activate vascular K(ATP) channels during hypoxia. To addres...

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Detalles Bibliográficos
Autores principales: Yang, Mingming, Dart, Caroline, Kamishima, Tomoko, Quayle, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664465/
https://www.ncbi.nlm.nih.gov/pubmed/33240653
http://dx.doi.org/10.7717/peerj.10344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664465/
https://www.ncbi.nlm.nih.gov/pubmed/33240653
http://dx.doi.org/10.7717/peerj.10344

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