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Lactic Acid and an Acidic Tumor Microenvironment suppress Anticancer Immunity

Immune evasion and altered metabolism, where glucose utilization is diverted to increased lactic acid production, are two fundamental hallmarks of cancer. Although lactic acid has long been considered a waste product of this alteration, it is now well accepted that increased lactic acid production a...

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Detalles Bibliográficos
Autores principales: Wang, Joy X., Choi, Stephen Y.C., Niu, Xiaojia, Kang, Ning, Xue, Hui, Killam, James, Wang, Yuzhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664620/
https://www.ncbi.nlm.nih.gov/pubmed/33171818
http://dx.doi.org/10.3390/ijms21218363