Lost in the Crowd: How Does Human 8-Oxoguanine DNA Glycosylase 1 (OGG1) Find 8-Oxoguanine in the Genome?

The most frequent DNA lesion resulting from an oxidative stress is 7,8-dihydro-8-oxoguanine (8-oxoG). 8-oxoG is a premutagenic base modification due to its capacity to pair with adenine. Thus, the repair of 8-oxoG is critical for the preservation of the genetic information. Nowadays, 8-oxoG is also...

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Detalles Bibliográficos
Autores principales: D’Augustin, Ostiane, Huet, Sébastien, Campalans, Anna, Radicella, Juan Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664663/
https://www.ncbi.nlm.nih.gov/pubmed/33171795
http://dx.doi.org/10.3390/ijms21218360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664663/
https://www.ncbi.nlm.nih.gov/pubmed/33171795
http://dx.doi.org/10.3390/ijms21218360

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