Apelin-13 Protects Dopaminergic Neurons against Rotenone—Induced Neurotoxicity through the AMPK/mTOR/ULK-1 Mediated Autophagy Activation

Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Several brain–gut peptides are able to exert neuroprotective effects on the nigrostriatal dopaminergic system. Apelin-13 is a neuropeptide, conveying potential neuroprotec...

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Detalles Bibliográficos
Autores principales: Chen, Peng, Wang, Youcui, Chen, Leilei, Song, Ning, Xie, Junxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664695/
https://www.ncbi.nlm.nih.gov/pubmed/33171641
http://dx.doi.org/10.3390/ijms21218376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664695/
https://www.ncbi.nlm.nih.gov/pubmed/33171641
http://dx.doi.org/10.3390/ijms21218376

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