Adsorption of Chiral [5]-Aza[5]helicenes on DNA Can Modify Its Hydrophilicity and Affect Its Chiral Architecture: A Molecular Dynamics Study

Helicenes are interesting chiral molecules without asymmetric carbon atoms but with intrinsic chirality. Functionalized 5-Aza[5]helicenes can form non-covalent complexes with anticancer drugs and therefore be potential carriers. The paper highlights the different structural selectivity for DNA bindi...

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Detalles Bibliográficos
Autores principales: Raffaini, Giuseppina, Mele, Andrea, Caronna, Tullio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664699/
https://www.ncbi.nlm.nih.gov/pubmed/33171884
http://dx.doi.org/10.3390/ma13215031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664699/
https://www.ncbi.nlm.nih.gov/pubmed/33171884
http://dx.doi.org/10.3390/ma13215031

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