Discovery of 12O—A Novel Oral Multi-Kinase Inhibitor for the Treatment of Solid Tumor

A novel series of pyrimidine-benzotriazole derivatives have been synthesized and evaluated for their anticancer activity against human solid tumor cell lines. The most promising molecule 12O was identified for its excellent antiproliferative activities, especially against the SiHa cell line with IC(...

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Detalles Bibliográficos
Autores principales: Fan, Yan, Huang, Zhi, Wang, Xiaoshuang, Ma, Yakun, Li, Yongtao, Yang, Shengyong, Shi, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664879/
https://www.ncbi.nlm.nih.gov/pubmed/33182255
http://dx.doi.org/10.3390/molecules25215199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664879/
https://www.ncbi.nlm.nih.gov/pubmed/33182255
http://dx.doi.org/10.3390/molecules25215199

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