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Different Sensitivity of Macrophages to Phospholipidosis Induction by Amphiphilic Cationic Drugs

Phospholipidosis (PLD), the intracellular accumulation of phospholipids, is an adaptive response to toxic stimuli and serves as an important parameter in the biological assessment of compounds. Cationic amphiphilic drugs are the main inducers of PLD and may impair the function of alveolar macrophage...

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Detalles Bibliográficos
Autores principales: Öhlinger, Kristin, Absenger-Novak, Markus, Meindl, Claudia, Ober, Jennifer, Fröhlich, Eleonore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664898/
https://www.ncbi.nlm.nih.gov/pubmed/33182310
http://dx.doi.org/10.3390/ijms21218391