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Intra-individual variability of eGFR trajectories in early diabetic kidney disease and lack of performance of prognostic biomarkers

Studies reporting on biomarkers aiming to predict adverse renal outcomes in patients with type 2 diabetes and kidney disease (DKD) conventionally define a surrogate endpoint either as a percentage of decrease of eGFR (e.g. ≥ 30%) or an absolute decline (e.g. ≥ 5 ml/min/year). The application of thos...

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Detalles Bibliográficos
Autores principales: Kerschbaum, Julia, Rudnicki, Michael, Dzien, Alexander, Dzien-Bischinger, Christine, Winner, Hannes, Heerspink, Hiddo Lambers, Rosivall, László, Wiecek, Andrzej, Mark, Patrick B., Eder, Susanne, Denicolò, Sara, Mayer, Gert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665005/
https://www.ncbi.nlm.nih.gov/pubmed/33184434
http://dx.doi.org/10.1038/s41598-020-76773-0