Acetylsalicylic acid and salicylic acid present anticancer properties against melanoma by promoting nitric oxide-dependent endoplasmic reticulum stress and apoptosis

Melanoma is the most aggressive and fatal type of skin cancer due to being highly proliferative. Acetylsalicylic acid (ASA; Aspirin) and salicylic acid (SA) are ancient drugs with multiple applications in medicine. Here, we showed that ASA and SA present anticancer effects against a murine model of...

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Detalles Bibliográficos
Autores principales: Ausina, Priscila, Branco, Jessica R., Demaria, Thainá M., Esteves, Amanda M., Leandro, João Gabriel B., Ochioni, Alan C., Mendonça, Ana Paula M., Palhano, Fernando L., Oliveira, Marcus F., Abou-Kheir, Wassim, Sola-Penna, Mauro, Zancan, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665072/
https://www.ncbi.nlm.nih.gov/pubmed/33184378
http://dx.doi.org/10.1038/s41598-020-76824-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665072/
https://www.ncbi.nlm.nih.gov/pubmed/33184378
http://dx.doi.org/10.1038/s41598-020-76824-6

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