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Induction of differentiation of the acute myeloid leukemia cell line (HL-60) by a securinine dimer

Differentiation therapy has been successfully applied clinically in cases of acute promyelocytic leukemia (APL), but few differentiation-induction agents other than all-trans retinoic acid (ATRA) have been discovered clinically. Based on our previously reported neuritogenic differentiation activity...

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Detalles Bibliográficos
Autores principales: Hou, Wen, Wang, Zhen-Ya, Lin, Jing, Chen, Wei-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665178/
https://www.ncbi.nlm.nih.gov/pubmed/33298839
http://dx.doi.org/10.1038/s41420-020-00354-3