Mucosal delivery of a multistage subunit vaccine promotes development of lung-resident memory T cells and affords interleukin-17-dependent protection against pulmonary tuberculosis

The development of effective vaccines against bacterial lung infections requires the induction of protective, pathogen-specific immune responses without deleterious inflammation within the pulmonary environment. Here, we made use of a polysaccharide-adjuvanted vaccine approach to elicit resident pul...

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Detalles Bibliográficos
Autores principales: Counoupas, Claudio, Ferrell, Kia C., Ashhurst, Anneliese, Bhattacharyya, Nayan D., Nagalingam, Gayathri, Stewart, Erica L., Feng, Carl G., Petrovsky, Nikolai, Britton, Warwick J., Triccas, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665186/
https://www.ncbi.nlm.nih.gov/pubmed/33298977
http://dx.doi.org/10.1038/s41541-020-00255-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665186/
https://www.ncbi.nlm.nih.gov/pubmed/33298977
http://dx.doi.org/10.1038/s41541-020-00255-7

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