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Knockdown lncRNA NEAT1 regulates the activation of microglia and reduces AKT signaling and neuronal apoptosis after cerebral ischemic reperfusion

Acute cerebral ischaemia may lead to serious consequences, including brain injury caused by uncontrolled reperfusion, which occurs when circulation is re-established. The long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) plays an important role in the immune system. However...

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Detalles Bibliográficos
Autores principales: Ni, Xunran, Su, Qian, Xia, Wenbo, Zhang, Yanli, Jia, Kejuan, Su, Zhiqiang, Li, Guozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665206/
https://www.ncbi.nlm.nih.gov/pubmed/33184298
http://dx.doi.org/10.1038/s41598-020-71411-1