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WNK regulates Wnt signalling and β-Catenin levels by interfering with the interaction between β-Catenin and GID

β-Catenin is an important component of the Wnt signalling pathway. As dysregulation or mutation of this pathway causes many diseases, including cancer, the β-Catenin level is carefully regulated by the destruction complex in the Wnt signalling pathway. However, the mechanisms underlying the regulati...

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Detalles Bibliográficos
Autores principales: Sato, Atsushi, Shimizu, Masahiro, Goto, Toshiyasu, Masuno, Hiroyuki, Kagechika, Hiroyuki, Tanaka, Nobuyuki, Shibuya, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665214/
https://www.ncbi.nlm.nih.gov/pubmed/33184430
http://dx.doi.org/10.1038/s42003-020-01386-2