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WNK regulates Wnt signalling and β-Catenin levels by interfering with the interaction between β-Catenin and GID
β-Catenin is an important component of the Wnt signalling pathway. As dysregulation or mutation of this pathway causes many diseases, including cancer, the β-Catenin level is carefully regulated by the destruction complex in the Wnt signalling pathway. However, the mechanisms underlying the regulati...
Autores principales: | Sato, Atsushi, Shimizu, Masahiro, Goto, Toshiyasu, Masuno, Hiroyuki, Kagechika, Hiroyuki, Tanaka, Nobuyuki, Shibuya, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665214/ https://www.ncbi.nlm.nih.gov/pubmed/33184430 http://dx.doi.org/10.1038/s42003-020-01386-2 |
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