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AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity

AKT, a serine threonine kinase, exists in three different isoforms and is known for regulating several biological processes including tumorigenesis. In this study, we investigated the expression and net effect of the individual isoforms in triple negative breast cancers and response to cisplatin tre...

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Detalles Bibliográficos
Autores principales: Wadhwa, Bhumika, Paddar, Masroor, Khan, Sameer, Mir, Sameer, A.Clarke, Philip, Grabowska, Anna M., Vijay, Devanahalli G., Malik, Fayaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665233/
https://www.ncbi.nlm.nih.gov/pubmed/33227065
http://dx.doi.org/10.18632/oncotarget.27746