T-cell redirecting bispecific antibodies targeting BCMA for the treatment of multiple myeloma

B-cell maturation antigen (BCMA)-targeting bispecific antibodies and bispecific T-cell engagers (BiTEs) redirect T-cells to BCMA-expressing multiple myeloma (MM) cells. These MM cells are subsequently eliminated via various mechanisms of action including the release of granzymes and perforins. Sever...

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Detalles Bibliográficos
Autores principales: Verkleij, Christie P.M., Frerichs, Kristine A., Broekmans, Marloes, Absalah, Saida, Maas-Bosman, Patricia W.C., Kruyswijk, Sandy, Nijhof, Inger S., Mutis, Tuna, Zweegman, Sonja, van de Donk, Niels W.C.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665238/
https://www.ncbi.nlm.nih.gov/pubmed/33227097
http://dx.doi.org/10.18632/oncotarget.27792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665238/
https://www.ncbi.nlm.nih.gov/pubmed/33227097
http://dx.doi.org/10.18632/oncotarget.27792

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