Systemic effects of missense mutations on SARS-CoV-2 spike glycoprotein stability and receptor-binding affinity

The spike (S) glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the binding to the permissive cells. The receptor-binding domain (RBD) of SARS-CoV-2 S protein directly interacts with the human angiotensin-converting enzyme 2 (ACE2) on the host cell membr...

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Detalles Bibliográficos
Autores principales: Teng, Shaolei, Sobitan, Adebiyi, Rhoades, Raina, Liu, Dongxiao, Tang, Qiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Case Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665319/
https://www.ncbi.nlm.nih.gov/pubmed/33006605
http://dx.doi.org/10.1093/bib/bbaa233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665319/
https://www.ncbi.nlm.nih.gov/pubmed/33006605
http://dx.doi.org/10.1093/bib/bbaa233

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