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A path towards SARS-CoV-2 attenuation: metabolic pressure on CTP synthesis rules the virus evolution
In the context of the COVID-19 pandemic, we describe here the singular metabolic background that constrains enveloped RNA viruses to evolve towards likely attenuation in the long term, possibly after a step of increased pathogenicity. Cytidine triphosphate (CTP) is at the crossroad of the processes...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665462/ https://www.ncbi.nlm.nih.gov/pubmed/33125064 http://dx.doi.org/10.1093/gbe/evaa229 |