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Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney

AIMS: Angiotensin-converting enzyme 2 (ACE2) is the cellular entry point for severe acute respiratory syndrome coronavirus (SARS-CoV-2)—the cause of coronavirus disease 2019 (COVID-19). However, the effect of renin-angiotensin system (RAS)-inhibition on ACE2 expression in human tissues of key releva...

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Detalles Bibliográficos
Autores principales: Jiang, Xiao, Eales, James M, Scannali, David, Nazgiewicz, Alicja, Prestes, Priscilla, Maier, Michelle, Denniff, Matthew, Xu, Xiaoguang, Saluja, Sushant, Cano-Gamez, Eddie, Wystrychowski, Wojciech, Szulinska, Monika, Antczak, Andrzej, Byars, Sean, Skrypnik, Damian, Glyda, Maciej, Król, Robert, Zywiec, Joanna, Zukowska-Szczechowska, Ewa, Burrell, Louise M, Woolf, Adrian S, Greenstein, Adam, Bogdanski, Pawel, Keavney, Bernard, Morris, Andrew P, Heagerty, Anthony, Williams, Bryan, Harrap, Stephen B, Trynka, Gosia, Samani, Nilesh J, Guzik, Tomasz J, Charchar, Fadi J, Tomaszewski, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665509/
https://www.ncbi.nlm.nih.gov/pubmed/33206176
http://dx.doi.org/10.1093/eurheartj/ehaa794