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Antidepressive effect of an inward rectifier K(+) channel blocker peptide, tertiapin-RQ
Renal outer medullary K(+) channel, ROMK (Kir1.1, kcnj1) is expressed in the kidney and brain, but its role in the central nervous system remains unknown. Recent studies suggested an involvement of the ROMK channel in mental diseases. Tertiapin (TPN) is a European honey bee venom peptide and is repo...
Autores principales: | Okada, Masayoshi, Kozaki, Ikkou, Honda, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665585/ https://www.ncbi.nlm.nih.gov/pubmed/33186384 http://dx.doi.org/10.1371/journal.pone.0233815 |
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