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The peroxisome proliferator-activated receptor gamma (PPARγ) agonist, rosiglitazone, ameliorates neurofunctional and neuroinflammatory abnormalities in a rat model of Gulf War Illness

BACKGROUND: Gulf War (GW) Illness (GWI) is a debilitating condition with a complex constellation of immune, endocrine and neurological symptoms, including cognitive impairment, anxiety and depression. We studied a novel model of GWI based on 3 known common GW exposures (GWE): (i) intranasal lipopoly...

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Detalles Bibliográficos
Autores principales: Keledjian, Kaspar, Tsymbalyuk, Orest, Semick, Stephen, Moyer, Mitchell, Negoita, Serban, Kim, Kevin, Ivanova, Svetlana, Gerzanich, Volodymyr, Simard, J. Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665704/
https://www.ncbi.nlm.nih.gov/pubmed/33186383
http://dx.doi.org/10.1371/journal.pone.0242427