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The peroxisome proliferator-activated receptor gamma (PPARγ) agonist, rosiglitazone, ameliorates neurofunctional and neuroinflammatory abnormalities in a rat model of Gulf War Illness
BACKGROUND: Gulf War (GW) Illness (GWI) is a debilitating condition with a complex constellation of immune, endocrine and neurological symptoms, including cognitive impairment, anxiety and depression. We studied a novel model of GWI based on 3 known common GW exposures (GWE): (i) intranasal lipopoly...
Autores principales: | Keledjian, Kaspar, Tsymbalyuk, Orest, Semick, Stephen, Moyer, Mitchell, Negoita, Serban, Kim, Kevin, Ivanova, Svetlana, Gerzanich, Volodymyr, Simard, J. Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665704/ https://www.ncbi.nlm.nih.gov/pubmed/33186383 http://dx.doi.org/10.1371/journal.pone.0242427 |
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