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A Systematic Literature Review and Meta-Analysis Describing the Prevalence of KRAS, NRAS, and BRAF Gene Mutations in Metastatic Colorectal Cancer

BACKGROUND: Tumors of the metastatic colorectal cancer (mCRC) patients that are wildtype (WT) for KRAS or NRAS mutations respond more favorably to anti-epidermal growth factor receptor (EGFR) treatments. Treatment guidelines now recommend that all mCRC patients have WT KRAS and NRAS tumor status con...

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Detalles Bibliográficos
Autores principales: Levin-Sparenberg, Elizabeth, Bylsma, Lauren C., Lowe, Kimberly, Sangare, Laura, Fryzek, Jon P., Alexander, Dominik D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665856/
https://www.ncbi.nlm.nih.gov/pubmed/33224365
http://dx.doi.org/10.14740/gr1167