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A Systematic Literature Review and Meta-Analysis Describing the Prevalence of KRAS, NRAS, and BRAF Gene Mutations in Metastatic Colorectal Cancer

BACKGROUND: Tumors of the metastatic colorectal cancer (mCRC) patients that are wildtype (WT) for KRAS or NRAS mutations respond more favorably to anti-epidermal growth factor receptor (EGFR) treatments. Treatment guidelines now recommend that all mCRC patients have WT KRAS and NRAS tumor status con...

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Detalles Bibliográficos
Autores principales:	Levin-Sparenberg, Elizabeth, Bylsma, Lauren C., Lowe, Kimberly, Sangare, Laura, Fryzek, Jon P., Alexander, Dominik D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elmer Press 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665856/ https://www.ncbi.nlm.nih.gov/pubmed/33224365 http://dx.doi.org/10.14740/gr1167

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