Homology-guided identification of a conserved motif linking the antiviral functions of IFITM3 to its oligomeric state

The interferon-inducible transmembrane (IFITM) proteins belong to the Dispanin/CD225 family and inhibit diverse virus infections. IFITM3 reduces membrane fusion between cells and virions through a poorly characterized mechanism. Mutation of proline-rich transmembrane protein 2 (PRRT2), a regulator o...

Descripción completa

Detalles Bibliográficos
Autores principales: Rahman, Kazi, Coomer, Charles A, Majdoul, Saliha, Ding, Selena Y, Padilla-Parra, Sergi, Compton, Alex A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665892/
https://www.ncbi.nlm.nih.gov/pubmed/33112230
http://dx.doi.org/10.7554/eLife.58537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665892/
https://www.ncbi.nlm.nih.gov/pubmed/33112230
http://dx.doi.org/10.7554/eLife.58537

Ejemplares similares