DNA mismatches reveal conformational penalties in protein-DNA recognition

Transcription factors (TF) recognize specific genomic sequences to regulate complex gene expression programs. Although it is well established that TFs bind specific DNA sequences using a combination of base readout and shape recognition, some fundamental aspects of protein-DNA binding remain poorly...

Descripción completa

Detalles Bibliográficos
Autores principales: Afek, Ariel, Shi, Honglue, Rangadurai, Atul, Sahay, Harshit, Senitzki, Alon, Xhani, Suela, Fang, Mimi, Salinas, Raul, Mielko, Zachery, Pufall, Miles A., Poon, Gregory M.K., Haran, Tali E., Schumacher, Maria A., Al-Hashimi, Hashim M., Gordan, Raluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666076/
https://www.ncbi.nlm.nih.gov/pubmed/33087930
http://dx.doi.org/10.1038/s41586-020-2843-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666076/
https://www.ncbi.nlm.nih.gov/pubmed/33087930
http://dx.doi.org/10.1038/s41586-020-2843-2

Ejemplares similares