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A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles
Detecting ligand-protein interactions in living cells is a fundamental challenge in molecular biology and drug research. Proteome-wide profiling of thermal stability as a function of ligand concentration promises to tackle this challenge. However, current data analysis strategies use preset threshol...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666118/ https://www.ncbi.nlm.nih.gov/pubmed/33188197 http://dx.doi.org/10.1038/s41467-020-19529-8 |