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Design and development of innovative microparticulate/nanoparticulate inhalable dry powders of a novel synthetic trifluorinated chalcone derivative and Nrf2 agonist

Chalcone derivatives are shown to possess excellent anti-inflammatory and anti-oxidant properties which are of great interest in treating respiratory diseases such as acute lung injury (ALI), acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and pulmonary fibr...

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Detalles Bibliográficos
Autores principales: Muralidharan, Priya, Jones, Brielle, Allaway, Graham, Biswal, Shyam S., Mansour, Heidi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666129/
https://www.ncbi.nlm.nih.gov/pubmed/33188247
http://dx.doi.org/10.1038/s41598-020-76585-2