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Scutellarin ameliorates pulmonary fibrosis through inhibiting NF-κB/NLRP3-mediated epithelial–mesenchymal transition and inflammation

Idiopathic pulmonary fibrosis (IPF) is featured with inflammation and extensive lung remodeling caused by overloaded deposition of extracellular matrix. Scutellarin is the major effective ingredient of breviscapine and its anti-inflammation efficacy has been reported before. Nevertheless, the impact...

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Detalles Bibliográficos
Autores principales: Peng, Ling, Wen, Li, Shi, Qing-Feng, Gao, Feng, Huang, Bin, Meng, Jie, Hu, Cheng-Ping, Wang, Chang-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666141/
https://www.ncbi.nlm.nih.gov/pubmed/33188176
http://dx.doi.org/10.1038/s41419-020-03178-2