Cargando…

Scutellarin ameliorates pulmonary fibrosis through inhibiting NF-κB/NLRP3-mediated epithelial–mesenchymal transition and inflammation

Idiopathic pulmonary fibrosis (IPF) is featured with inflammation and extensive lung remodeling caused by overloaded deposition of extracellular matrix. Scutellarin is the major effective ingredient of breviscapine and its anti-inflammation efficacy has been reported before. Nevertheless, the impact...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peng, Ling, Wen, Li, Shi, Qing-Feng, Gao, Feng, Huang, Bin, Meng, Jie, Hu, Cheng-Ping, Wang, Chang-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666141/ https://www.ncbi.nlm.nih.gov/pubmed/33188176 http://dx.doi.org/10.1038/s41419-020-03178-2

Ejemplares similares

Cepharanthine Ameliorates Pulmonary Fibrosis by Inhibiting the NF-κB/NLRP3 Pathway, Fibroblast-to-Myofibroblast Transition and Inflammation
por: Chen, Guangrui, et al.
Publicado: (2023)

NecroX-5 ameliorates bleomycin-induced pulmonary fibrosis via inhibiting NLRP3-mediated epithelial–mesenchymal transition
por: Min, Li, et al.
Publicado: (2022)

Mesenchymal stem cells ameliorate silica‐induced pulmonary fibrosis by inhibition of inflammation and epithelial‐mesenchymal transition
por: Wei, Jingjing, et al.
Publicado: (2021)

Astragalus polysaccharides attenuate pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition and NF-κB pathway activation
por: Zhang, Rui, et al.
Publicado: (2020)

Anti-Fibrosis Effect of Scutellarin via Inhibition of Endothelial–Mesenchymal Transition on Isoprenaline-Induced Myocardial Fibrosis in Rats
por: Zhou, Hao, et al.
Publicado: (2014)

Coal dust nanoparticles induced pulmonary fibrosis by promoting inflammation and epithelial-mesenchymal transition via the NF-κB/NLRP3 pathway driven by IGF1/ROS-mediated AKT/GSK3β signals
por: Zhang, Yinci, et al.
Publicado: (2022)

Polydatin ameliorates pulmonary fibrosis by suppressing inflammation and the epithelial mesenchymal transition via inhibiting the TGF-β/Smad signaling pathway
por: Qiu, Yue, et al.
Publicado: (2019)

HLJ2 Effectively Ameliorates Colitis-Associated Cancer via Inhibition of NF-κB and Epithelial–Mesenchymal Transition
por: Song, Huachen, et al.
Publicado: (2020)

The Role of NLRP3 Inflammasome Activation in the Epithelial to Mesenchymal Transition Process During the Fibrosis
por: Alyaseer, Amani Abraheem Alsadiq, et al.
Publicado: (2020)

Epithelial–Mesenchymal Transition in the Pathogenesis of Idiopathic Pulmonary Fibrosis
por: Salton, Francesco, et al.
Publicado: (2019)

Emodin ameliorates bleomycin-induced pulmonary fibrosis in rats by suppressing epithelial-mesenchymal transition and fibroblast activation
por: Guan, Ruijuan, et al.
Publicado: (2016)

Berberine Ameliorates Inflammation in Acute Lung Injury via NF-κB/Nlrp3 Signaling Pathway
por: Chen, Jiyu, et al.
Publicado: (2022)

NF-κB signaling in neoplastic transition from epithelial to mesenchymal phenotype
por: Oh, Amy, et al.
Publicado: (2023)

Scutellarin Ameliorates Renal Injury via Increasing CCN1 Expression and Suppressing NLRP3 Inflammasome Activation in Hyperuricemic Mice
por: Li, Guozheng, et al.
Publicado: (2020)

Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: potential roles in the inhibition of epithelial–mesenchymal transition and fibroblast activation
por: Chen, Y-L, et al.
Publicado: (2013)

Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition
por: Kyung, Sun Young, et al.
Publicado: (2018)

Role of Ferroptosis in Regulating the Epithelial–Mesenchymal Transition in Pulmonary Fibrosis
por: Ling, Hong, et al.
Publicado: (2023)

Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis
por: Liu, Yi, et al.
Publicado: (2018)

β-Caryophyllene Ameliorates MSU-Induced Gouty Arthritis and Inflammation Through Inhibiting NLRP3 and NF-κB Signal Pathway: In Silico and In Vivo
por: Li, Wan-Yang, et al.
Publicado: (2021)

NF-κB–Dependent Snail Expression Promotes Epithelial–Mesenchymal Transition in Mastitis
por: Liu, Haokun, et al.
Publicado: (2021)

Vincamine Ameliorates Epithelial-Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis in Rats; Targeting TGF-β/MAPK/Snai1 Pathway
por: Alaaeldin, Rania, et al.
Publicado: (2023)

Calpain inhibition attenuates bleomycin-induced pulmonary fibrosis via switching the development of epithelial-mesenchymal transition
por: Liu, Yuan, et al.
Publicado: (2018)

Particulate matters increase epithelial-mesenchymal transition and lung fibrosis through the ETS-1/NF-κB-dependent pathway in lung epithelial cells
por: Chen, Yu-Chen, et al.
Publicado: (2020)

Fuzheng Huayu Recipe Ameliorates Liver Fibrosis by Restoring Balance between Epithelial-to-Mesenchymal Transition and Mesenchymal-to-Epithelial Transition in Hepatic Stellate Cells
por: Pan, Qin, et al.
Publicado: (2015)

Melatonin Inhibits Endoplasmic Reticulum Stress and Epithelial-Mesenchymal Transition during Bleomycin-Induced Pulmonary Fibrosis in Mice
por: Zhao, Hui, et al.
Publicado: (2014)

Osthole Ameliorates Renal Fibrosis in Mice by Suppressing Fibroblast Activation and Epithelial-Mesenchymal Transition
por: Zhang, Suping, et al.
Publicado: (2018)

LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy
por: Yi, Hong, et al.
Publicado: (2017)

Canagliflozin Ameliorates NLRP3 Inflammasome-Mediated Inflammation Through Inhibiting NF-κB Signaling and Upregulating Bif-1
por: Niu, Yaoyun, et al.
Publicado: (2022)

Nanoapproaches to Modifying Epigenetics of Epithelial Mesenchymal Transition for Treatment of Pulmonary Fibrosis
por: Skibba, Melissa, et al.
Publicado: (2020)

Iron metabolism regulation of epithelial-mesenchymal transition in idiopathic pulmonary fibrosis
por: Han, Yi, et al.
Publicado: (2021)

Lipocalin2 suppresses metastasis of colorectal cancer by attenuating NF-κB-dependent activation of snail and epithelial mesenchymal transition
por: Feng, Meibao, et al.
Publicado: (2016)

Sorafenib Ameliorates Renal Fibrosis through Inhibition of TGF-β-Induced Epithelial-Mesenchymal Transition
por: Jia, Lining, et al.
Publicado: (2015)

Human umbilical cord mesenchymal stem cell conditioned medium attenuates renal fibrosis by reducing inflammation and epithelial-to-mesenchymal transition via the TLR4/NF-κB signaling pathway in vivo and in vitro
por: Liu, Bo, et al.
Publicado: (2018)

Yangyin Yiqi Mixture Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Rats through Inhibiting TGF-β1/Smad Pathway and Epithelial to Mesenchymal Transition
por: Meng, Lihong, et al.
Publicado: (2019)

Oral Scutellarin Treatment Ameliorates Retinal Thinning and Visual Deficits in Experimental Glaucoma
por: Zhu, Jingyuan, et al.
Publicado: (2021)

ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-κB-dependent activation of Snail
por: Cichon, Magdalena A., et al.
Publicado: (2014)

Epithelial–Mesenchymal Transition: A Major Pathogenic Driver in Idiopathic Pulmonary Fibrosis?
por: Salton, Francesco, et al.
Publicado: (2020)

Molecular mechanisms of COVID-19-induced pulmonary fibrosis and epithelial-mesenchymal transition
por: Pi, Peng, et al.
Publicado: (2023)

Scutellarin ameliorates neonatal hypoxic-ischemic encephalopathy associated with GAP43-dependent signaling pathway
por: Niu, Rui-Ze, et al.
Publicado: (2021)

LncRNA XIST mediates bovine mammary epithelial cell inflammatory response via NF‐κB/NLRP3 inflammasome pathway
por: Ma, Mengru, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_slbb8u561thragd75im0udboga