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ATAC-seq with unique molecular identifiers improves quantification and footprinting

ATAC-seq (Assay for Transposase-Accessible Chromatin with high-throughput sequencing) provides an efficient way to analyze nucleosome-free regions and has been applied widely to identify transcription factor footprints. Both applications rely on the accurate quantification of insertion events of the...

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Detalles Bibliográficos
Autores principales: Zhu, Tao, Liao, Keyan, Zhou, Rongfang, Xia, Chunjiao, Xie, Weibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666144/
https://www.ncbi.nlm.nih.gov/pubmed/33188264
http://dx.doi.org/10.1038/s42003-020-01403-4