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ppGpp functions as an alarmone in metazoa

Guanosine 3′,5′-bis(pyrophosphate) (ppGpp) functions as a second messenger in bacteria to adjust their physiology in response to environmental changes. In recent years, the ppGpp-specific hydrolase, metazoan SpoT homolog-1 (Mesh1), was shown to have important roles for growth under nutrient deficien...

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Detalles Bibliográficos
Autores principales: Ito, Doshun, Kawamura, Hinata, Oikawa, Akira, Ihara, Yuta, Shibata, Toshio, Nakamura, Nobuhiro, Asano, Tsunaki, Kawabata, Shun-Ichiro, Suzuki, Takashi, Masuda, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666150/
https://www.ncbi.nlm.nih.gov/pubmed/33188280
http://dx.doi.org/10.1038/s42003-020-01368-4