Ready-to-use nanopore platform for the detection of any DNA/RNA oligo at attomole range using an Osmium tagged complementary probe

Nanopores can serve as single molecule sensors. We exploited the MinION, a portable nanopore device from Oxford Nanopore Technologies, and repurposed it to detect any DNA/RNA oligo (target) in a complex mixture by conducting voltage-driven ion-channel measurements. The detection and quantitation of...

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Detalles Bibliográficos
Autores principales: Kang, Albert S. W., Bernasconi, Janette G., Jack, William, Kanavarioti, Anastassia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666163/
https://www.ncbi.nlm.nih.gov/pubmed/33188229
http://dx.doi.org/10.1038/s41598-020-76667-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666163/
https://www.ncbi.nlm.nih.gov/pubmed/33188229
http://dx.doi.org/10.1038/s41598-020-76667-1

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