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Acquired dysregulation of dopamine homeostasis reproduces features of Parkinson’s disease

The catecholamine neurotransmitter dopamine has the potential to act as an endogenous neurotoxin when its vesicular sequestration is dysregulated. Despite postmortem analyses from patients with Parkinson’s disease that demonstrate decreased vesicular sequestration of dopamine with a corresponding in...

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Detalles Bibliográficos
Autores principales: Bucher, Meghan L., Barrett, Caitlyn W., Moon, Connor J., Mortimer, Amanda D., Burton, Edward A., Timothy Greenamyre, J., Hastings, Teresa G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666186/
https://www.ncbi.nlm.nih.gov/pubmed/33298952
http://dx.doi.org/10.1038/s41531-020-00134-x