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Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities

Necrotizing enterocolitis (NEC) is a severe, currently untreatable intestinal disease that predominantly affects preterm infants and is driven by poorly characterized inflammatory pathways. Here, human and murine NEC intestines exhibit an unexpected predominance of type 3/T(H)17 polarization. In mur...

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Detalles Bibliográficos
Autores principales: Cho, Steven X., Rudloff, Ina, Lao, Jason C., Pang, Merrin A., Goldberg, Rimma, Bui, Christine B., McLean, Catriona A., Stock, Magdalena, Klassert, Tilman E., Slevogt, Hortense, Mangan, Niamh E., Cheng, Wei, Fischer, Doris, Gfroerer, Stefan, Sandhu, Manjeet K., Ngo, Devi, Bujotzek, Alexander, Lariviere, Laurent, Schumacher, Felix, Tiefenthaler, Georg, Beker, Friederike, Collins, Clare, Kamlin, C. Omar F., König, Kai, Malhotra, Atul, Tan, Kenneth, Theda, Christiane, Veldman, Alex, Ellisdon, Andrew M., Whisstock, James C., Berger, Philip J., Nold-Petry, Claudia A., Nold, Marcel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666196/
https://www.ncbi.nlm.nih.gov/pubmed/33188181
http://dx.doi.org/10.1038/s41467-020-19400-w