Cargando…
Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities
Necrotizing enterocolitis (NEC) is a severe, currently untreatable intestinal disease that predominantly affects preterm infants and is driven by poorly characterized inflammatory pathways. Here, human and murine NEC intestines exhibit an unexpected predominance of type 3/T(H)17 polarization. In mur...
Autores principales: | Cho, Steven X., Rudloff, Ina, Lao, Jason C., Pang, Merrin A., Goldberg, Rimma, Bui, Christine B., McLean, Catriona A., Stock, Magdalena, Klassert, Tilman E., Slevogt, Hortense, Mangan, Niamh E., Cheng, Wei, Fischer, Doris, Gfroerer, Stefan, Sandhu, Manjeet K., Ngo, Devi, Bujotzek, Alexander, Lariviere, Laurent, Schumacher, Felix, Tiefenthaler, Georg, Beker, Friederike, Collins, Clare, Kamlin, C. Omar F., König, Kai, Malhotra, Atul, Tan, Kenneth, Theda, Christiane, Veldman, Alex, Ellisdon, Andrew M., Whisstock, James C., Berger, Philip J., Nold-Petry, Claudia A., Nold, Marcel F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666196/ https://www.ncbi.nlm.nih.gov/pubmed/33188181 http://dx.doi.org/10.1038/s41467-020-19400-w |
Ejemplares similares
-
The immunological landscape in necrotising enterocolitis
por: Cho, Steven X., et al.
Publicado: (2016) -
Parsing the IL-37-Mediated Suppression of Inflammasome Function
por: Rudloff, Ina, et al.
Publicado: (2020) -
Protein C preserves microcirculation in a model of neonatal septic shock
por: Fischer, Doris, et al.
Publicado: (2009) -
Refining anti‐inflammatory therapy strategies for bronchopulmonary dysplasia
por: Rudloff, Ina, et al.
Publicado: (2016) -
Circulating Interleukin-37 Levels in Healthy Adult Humans – Establishing a Reference Range
por: Santarelli, Danielle M., et al.
Publicado: (2021)