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All atom insights into the impact of crowded environments on protein stability by NMR spectroscopy

The high density of macromolecules affecting proteins due to volume exclusion has been discussed in theory but numerous in vivo experiments cannot be sufficiently understood taking only pure entropic stabilization into account. Here, we show that the thermodynamic stability of a beta barrel protein...

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Detalles Bibliográficos
Autores principales: Köhn, Birgit, Kovermann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666220/
https://www.ncbi.nlm.nih.gov/pubmed/33188202
http://dx.doi.org/10.1038/s41467-020-19616-w