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YTHDC1 mitigates ischemic stroke by promoting Akt phosphorylation through destabilizing PTEN mRNA
YTH Domain Containing 1 (YTHDC1) is one of the m(6)A readers that is essential for oocyte development and tumor progression. The role of YTHDC1 in neuronal survival and ischemic stroke is unknown. Here, we found that YTHDC1 was unregulated in the early phase of ischemic stroke. Knockdown of YTHDC1 e...
Autores principales: | Zhang, Zhaolong, Wang, Qiuhan, Zhao, Xiaolong, Shao, Liming, Liu, Guoping, Zheng, Xuan, Xie, Lingling, Zhang, Yan, Sun, Chengjian, Xu, Rui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666223/ https://www.ncbi.nlm.nih.gov/pubmed/33188203 http://dx.doi.org/10.1038/s41419-020-03186-2 |
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