Targeting endothelin 1 receptor-miR-200b/c-ZEB1 circuitry blunts metastatic progression in ovarian cancer

Identification of regulatory mechanisms underlying the poor prognosis of ovarian cancer is necessary for diagnostic and therapeutic implications. Here we show that endothelin A receptor (ET(A)R) and ZEB1 expression is upregulated in mesenchymal ovarian cancer and correlates with poor prognosis. Nota...

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Detalles Bibliográficos
Autores principales: Sestito, Rosanna, Cianfrocca, Roberta, Tocci, Piera, Rosanò, Laura, Sacconi, Andrea, Blandino, Giovanni, Bagnato, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666224/
https://www.ncbi.nlm.nih.gov/pubmed/33188287
http://dx.doi.org/10.1038/s42003-020-01404-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666224/
https://www.ncbi.nlm.nih.gov/pubmed/33188287
http://dx.doi.org/10.1038/s42003-020-01404-3

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