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Glycan-Based Near-infrared Fluorescent (NIRF) Imaging of Gastrointestinal Tumors: a Preclinical Proof-of-Concept In Vivo Study

PURPOSE: Aberrantly expressed glycans in cancer are of particular interest for tumor targeting. This proof-of-concept in vivo study aims to validate the use of aberrant Lewis glycans as target for antibody-based, real-time imaging of gastrointestinal cancers. PROCEDURES: Immunohistochemical (IHC) st...

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Detalles Bibliográficos
Autores principales: Houvast, Ruben D., Baart, Victor M., Bhairosingh, Shadhvi S., Cordfunke, Robert A., Chua, Jia Xin, Vankemmelbeke, Mireille, Parsons, Tina, Kuppen, Peter J. K., Durrant, Lindy G., Vahrmeijer, Alexander L., Sier, Cornelis F. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666282/
https://www.ncbi.nlm.nih.gov/pubmed/32780212
http://dx.doi.org/10.1007/s11307-020-01522-8