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Glycan-Based Near-infrared Fluorescent (NIRF) Imaging of Gastrointestinal Tumors: a Preclinical Proof-of-Concept In Vivo Study
PURPOSE: Aberrantly expressed glycans in cancer are of particular interest for tumor targeting. This proof-of-concept in vivo study aims to validate the use of aberrant Lewis glycans as target for antibody-based, real-time imaging of gastrointestinal cancers. PROCEDURES: Immunohistochemical (IHC) st...
Autores principales: | Houvast, Ruben D., Baart, Victor M., Bhairosingh, Shadhvi S., Cordfunke, Robert A., Chua, Jia Xin, Vankemmelbeke, Mireille, Parsons, Tina, Kuppen, Peter J. K., Durrant, Lindy G., Vahrmeijer, Alexander L., Sier, Cornelis F. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666282/ https://www.ncbi.nlm.nih.gov/pubmed/32780212 http://dx.doi.org/10.1007/s11307-020-01522-8 |
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