Nintedanib and a bi-specific anti-VEGF/Ang2 nanobody selectively prevent brain metastases of lung adenocarcinoma cells

Brain metastases (BM) are an ever-increasing challenge in oncology, threatening quality of life and survival of many cancer patients. The majority of BM originate from lung adenocarcinoma, and stage III patients have a risk of 40–50% to develop BM in the first years of disease onset. As therapeutic...

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Detalles Bibliográficos
Autores principales: Kovalchuk, Bogdana, Berghoff, Anna S., Karreman, Matthia A., Frey, Katharina, Piechutta, Manuel, Fischer, Manuel, Grosch, Julia, Heiland, Sabine, Breckwoldt, Michael O., Hilberg, Frank, Wick, Wolfgang, Winkler, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666285/
https://www.ncbi.nlm.nih.gov/pubmed/32918638
http://dx.doi.org/10.1007/s10585-020-10055-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666285/
https://www.ncbi.nlm.nih.gov/pubmed/32918638
http://dx.doi.org/10.1007/s10585-020-10055-x

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