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Evaluating Brightness and Spectral Properties of Click Beetle and Firefly Luciferases Using Luciferin Analogues: Identification of Preferred Pairings of Luciferase and Substrate for In Vivo Bioluminescence Imaging

PURPOSE: Currently, a variety of red and green beetle luciferase variants are available for bioluminescence imaging (BLI). In addition, new luciferin analogues providing longer wavelength luminescence have been developed that show promise for improved deep tissue imaging. However, a detailed assessm...

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Detalles Bibliográficos
Autores principales: Zambito, Giorgia, Gaspar, Natasa, Ridwan, Yanto, Hall, Mary P., Shi, Ce, Kirkland, Thomas A., Encell, Lance P., Löwik, Clemens, Mezzanotte, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666294/
https://www.ncbi.nlm.nih.gov/pubmed/32926287
http://dx.doi.org/10.1007/s11307-020-01523-7