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A simple and robust cell-based assay for the discovery of novel cytokinesis inhibitors

Cytokinesis is the last step of mitotic cell division that separates the cytoplasm of dividing cells. Small molecule inhibitors targeting either the elements of the regulatory pathways controlling cytokinesis, or the terminal effectors have been of interest as potential drug candidates for the treat...

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Detalles Bibliográficos
Autores principales: Radnai, Laszlo, Stremel, Rebecca F., Vaissiere, Thomas, Lin, Li, Cameron, Michael, Martin, William H., Rumbaugh, Gavin, Kamenecka, Theodore M., Griffin, Patrick R., Miller, Courtney A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Biological Methods 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666332/
https://www.ncbi.nlm.nih.gov/pubmed/33204739
http://dx.doi.org/10.14440/jbm.2020.335