The Hsp40 Mas5 Connects Protein Quality Control and the General Stress Response through the Thermo-sensitive Pyp1

Upon heat shock, the fission yeast Hsp40 chaperone Mas5 drives temperature-sensitive proteins toward protein aggregate centers (PACs) to avoid their degradation until lower temperatures favor their refolding. We show here that cells lacking Mas5 are resistant to oxidative stress. Components of the g...

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Detalles Bibliográficos
Autores principales: Boronat, Susanna, Marte, Luis, Vega, Montserrat, García-Santamarina, Sarela, Cabrera, Margarita, Ayté, José, Hidalgo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666349/
https://www.ncbi.nlm.nih.gov/pubmed/33225241
http://dx.doi.org/10.1016/j.isci.2020.101725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666349/
https://www.ncbi.nlm.nih.gov/pubmed/33225241
http://dx.doi.org/10.1016/j.isci.2020.101725

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